Compared to lean women that were physically active there was nearly a two and half-fold increase in risk of death for obese and inactive women.  The researchers estimated that excess weight (BMI over 25) and physical inactivity (less than 3.5 hours per week) accounted for thirty one percent of all premature deaths among the study participants with fifty nine percent of the deaths attributable to cardiovascular disease and twenty one percent from cancer among the non-smoking women. During the twenty four year span of the study, 10,282 deaths occurred; 2,370 from cardiovascular disease, 5,223 from cancer and 2,689 from other causes.  

“It is clear that both exercise and weight are important for health and longevity,” said Frank Hu, lead author of the study and an associate professor of nutrition and epidemiology at the Harvard School of Public Health.

“There is no question that one should be as active as possible no matter what your weight is, but it is equally important to maintain a healthy weight and prevent weight gain through lifestyle and diet.”

Funding for the study was provided by grants from the National Institutes of Health.

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