working out in the gym
 

genetic factors and weight gain in middle age

 

your  genes and how they effect your weight


A new study indicates that genes may explain about fifty percent of weight gain that begins in middle age.

Researchers studied sets of twins who served in the military during the Vietnam War. Some of the twins were identical and shared the same genes, and the others were non-identical twins.

 


After twenty years of follow-up, the study now shows that genes account for about 1/2 of the weight gain among the men. Environmental factors, such as exercise and diet account for the other 1/2.

Researchers say the findings may help explain why some people find it hard to lose weight.

"We're not acknowledging the strength of genetic factors in our weight loss strategies," says James C. Romeis, PhD, professor of health services research at Saint Louis University School of Public Health, in a news release. "You've got this genetic thing working against you that helps to explain why you're so heavy and why you may fail at
weight loss programs and diets."


Weight Gain May Be In The Genes

In the study, which appeared in a recent issue of the journal Twin Research, researchers studied nearly 8,000 middle-aged, middle-class male twins who enlisted in the U.S. military during the late 1960s.

At the time of their  enlistment as young men more than 3/4s of them were considered normal weight, 17 percent were overweight, and 2.5 percent were obese or severely obese.

 

Twenty years later, less than half of the men were still considered normal weight. Meanwhile, more than half had become overweight.

The study showed that about 50 percent of the weight differences among the men appeared to be caused by genetic factors. Other aspects of their lifestyle and environment accounted for the rest.

Romeis says the influence of these environmental factors increases with age and puts people with a genetic disposition toward weight gain at a higher risk.

Although genetics may help to explain why some men gain weight more easily and have a harder time losing it, researchers say it should not stop them from trying to maintain a healthy weight, because weight gain doesn't just happen overnight.

"Weight gain appears to increase gradually," says Romeis. "For these guys, it's at about thirty years of age. Your behavior changes at thirty; you become more sedentary. At some point this tips into being overweight. Those who are overweight tip into becoming obese. It's slow, incremental change."

 

"While genetic vulnerability has probably not changed during the past few years, environments have, thus allowing for the genetic vulnerability to be expressed as what appears to be an alarming rate of increase," says Romeis.

"Losing weight is going to be a lot of work for these men," he says. "Treatments and public health interventions need to recognize the magnitude of genetic factors if
long-term and short-term interventions are to be effective."

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